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UPDATE: Left lane now open, two other lanes remain closed, according to DOTD at 12:15 p.m.

Interstate 10 east in Baton Rouge is closed past Siegen Lane after a multi-vehicle crash that happened at 11 a.m., officials said Thursday.Ìý

EMS transported five people to the hospital — one in critical condition, two in serious condition and two with minor injuries, an EMS spokesperson said.

Two of the injured were children, EMS said.Ìý

Congestion at about 11:30 a.m. was approaching Bluebonnet Boulevard, the state Department of Transportation and Development said.Ìý

"Motorists are advised to use an alternate route," DOTD said in an online post.

Multiple agencies are responding to the scene, the St. George Fire Department said online.Ìý

This is a developing story.Ìý

Email Ellyn Couvillion at ecouvillion@theadvocate.com.